Adverse Outcomes Increased With SARS-CoV-2 Infection During Pregnancy


WEDNESDAY, JANUARY 18, 2023 (HealthDay News) — Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy increases maternal mortality, maternal morbidity, and mortality, according to a study published online. Associated with increased risk of neonatal morbidity. January 16th BMJ Global Health.

Emily R. Smith, Ph.D., M.P.H., and colleagues at the Milken Institute School of Public Health, George Washington University, Washington, DC, screened ongoing studies in a prospective meta-analysis. Individual participant data were pooled to estimate absolute and relative risks of adverse outcomes in pregnant women with SARS-CoV-2 infection. A total of 137 studies were screened, including 12 of her 13,136 pregnant women from 12 countries.

Researchers found that compared with uninfected pregnant women, pregnant women infected with SARS-CoV-2 were more likely to die during maternal death, be admitted to intensive care, use a ventilator, receive critical care, We found a significantly higher risk of being diagnosed with pneumonia and thromboembolism. Disease (relative risk, 7.68, 3.81, 15.23, 5.48, 23.46, and 5.50, respectively). Newborns born to women with SARS-CoV-2 infection are more likely to be admitted to a neonatal care unit after birth, are born preterm or moderately preterm, and are born with low birth weight (relative risks, 1.86, 1.71, 2.92, and 1.19, respectively). No association with infection due to stillbirth was seen. Risk of bias was generally low or moderate.

“These findings highlight the need for global efforts to prevent COVID-19 during pregnancy through targeted administration of vaccines and non-pharmaceutical interventions,” the authors wrote. increase.

Several authors disclosed financial ties to the pharmaceutical industry.

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