Mediterranean diet linked to lower risk for adverse pregnancy outcomes


January 3, 2023

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Disclosure:
Makarem reports that he has received grants from the American Heart Association and the NIH outside of research.


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Women who adhered to a Mediterranean diet had a nearly 30 percent lower risk of pre-eclampsia than those who did not, according to a new study published in . JAMA network open.

A Mediterranean diet high in fruits, leafy green vegetables, nuts, cereals and extra virgin olive oil and moderate in dairy, fish and other meats was associated with improved cognitive function and risk of frailty. associated with decline.It was also named the best all-around meal US News & World Report the past few years.

Data source: Makarem N, et al. JAMA net opened. 2022;10.1001/jamanetworkopen.2022.48165.

Dr. Noor Makarem, MSc, Assistant Professor of Epidemiology at the Columbia Mailman School of Public Health and colleagues are currently conducting research to better understand “whether conformity to pre- and post-conception Mediterranean dietary patterns influences the risk of adverse pregnancy outcomes (APOs).” We conducted a study of

The analysis included data from 7,798 pregnant women. A total of 19.5% of individuals were obese, 16.6% were Hispanic, and 9.7% were her 35 years or older. Macarem and her colleagues scored each mother on a scale of 0 to 9 points based on adherence to the diet, with 6 to 9 constituting a ‘high Mediterranean diet score’.

Overall, the researchers found that stronger adherence to a Mediterranean diet was associated with lower risk of APO, defined as the development of pre-eclampsia or eclampsia, preterm birth, gestational diabetes, gestational hypertension, stillbirth or sub-pregnancy delivery. I found that it is related to Infants of age – There is “dose-response-related evidence,” suggesting that “women who were most consistent with this dietary pattern before conception had the lowest risk of developing APO.”

The average score they found was 4.3 points. Around the time of conception:

  • 30.6%, or 2,388 participants, showed high agreement on diet.
  • 31.2%, or 2,430 participants, showed moderate agreement.When
  • Concordance was low at 38.2%, or 2,980 participants.

High and low scores were associated with 37% lower odds of gestational diabetes (adjusted OR = 0.63; 95% CI, 0.44-0.9) and 28% lower odds of preeclampsia or eclampsia (aOR = 0.72; 95% CI , 0.55–0.93), and 21% lower odds for any APO (aOR = 0.79; 95% CI, 0.68–0.92).

The researchers found no significant differences by race, ethnicity, or pre-pregnancy BMI, but noted that “the association was stronger in women aged 35 years or older” (aOR = 0.54; 95 %CI, 0.34-0.84).

“This multicenter, population-based study validates that healthier dietary patterns are associated with reduced risk of adverse pregnancy outcomes, most interestingly, pre-eclampsia 28 % low.” Natalie Bello, MD, MPH, “Importantly, there are significant differences between the Mediterranean diet and a reduced risk of adverse effects of pregnancy,” said the senior and corresponding author of the study, who is the director of the hypertension study at the Smithart Institute in Los Angeles. This relationship was found in geographically, racially, and ethnically diverse populations.”

To assess whether pre- and post-conception dietary changes can reduce the risk of APO and downstream associations with risk factors for cardiovascular disease and future development of overt disease, the investigators Intervention studies are needed.

“Together, our findings suggest that adoption of a Mediterranean dietary pattern represents an important lifestyle approach for the prevention of APO in U.S. women, particularly those of older maternal age who are at high risk for APO.” “Our findings suggest that the Mediterranean dietary pattern plays an important role in maintaining women’s health throughout their lives, including during pregnancy,” they wrote. It shows that there is growing evidence that they may be doing so.”

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